Hotel Casa Santo Domingo hero

Hotel Casa Santo Domingo

3a Calle Oriente 28 A, Antigua Guatemala, Guatemala
Condé Nast Readers' Choice '22
Google 4.7
Overall 71
Lowest upcoming
$140
27 May 2026
Highest upcoming
$349
22 Sep 2026
Median nightly
$198
across 365 upcoming days
Cheapest week
28 Jun to 4 Jul
29% below annual median

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Cheapest week ahead: 28 Jun–4 Jul 2026 at $140/night (29% below median)

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Review

Synthesized from Condé Nast Traveler
Condé Nast Readers' Choice 2022 · 2021 · 2017

Character and identity

Set in the cobblestoned heart of Antigua, 45 minutes from Guatemala City's airport, this 128-room hotel occupies a 16th-century friary and wears its history openly: stone arches, candlelit corridors, archaeological fragments, and an on-site museum displaying colonial sculpture and religious silver recovered from the grounds. Rooms are restrained, with wood-beamed ceilings, fireplaces, and earth-toned furnishings that defer to the architecture. El Refectorio handles three meals of local and international cooking, while El Tenedor de Cerro pairs pasta and pizza with panoramic views of the Agua, Fuego, and Acatenango volcanoes. A spa, outdoor pool, and gracious, attentive service round out the experience.

Who's it for

Best for:
Couples and culturally curious travellers who want Antigua's colonial atmosphere built into the fabric of their stay, with museum-grade interiors, volcano views, and walkable access to the old city. History buffs, honeymooners, and design-minded guests who value patina and place over slick contemporary polish will feel at home.

Should look elsewhere:
Travellers wanting beach access, resort-scale leisure, or sleek modern rooms with bright contemporary design should look elsewhere. The convent setting means dim, atmospheric interiors and simple furnishings rather than plush luxury, and families chasing kids' clubs or marine activities won't find them here.

Bottom line

What you're paying for is the building itself: a working friary transformed into a hotel where the architecture, gardens, and museum carry the experience. Book a room with a working fireplace and wood-beamed ceiling, dine at El Tenedor de Cerro for the volcano view at sunset, and plan at least two nights so Antigua's churches and markets get the time they deserve.

Location

3a Calle Oriente 28 A, Antigua Guatemala, Guatemala · 10 nearest tracked hotels

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Amenities

18 features
Wi-Fi
Restaurant
Bar
Room service
Breakfast
Breakfast buffet
Front desk
Full service laundry
Pool
Hot tub
Kid-friendly
Fitness center

Practical info